BETTER
FASTER
ECONOMICAL

PERSONALIZATION WITHIN GUIDELINES

  • A comprehensive test to analyse actionable therapy options using guideline recommended genes in solid tumors.
  • Analysis by our CLIA / CAP accredited laboratory.
  • Covers all immunotherapy related bio-markers such as PD-L1, MSI and TMB.
  • Wholesome analysis of more than 417 genes enables use emergent of FDA approved therapies.

PERSONALIZATION WITHIN GUIDELINES

  • A comprehensive test to analyse actionable therapy options using guideline recommended genes in solid tumors.
  • Analysis by our CLIA / CAP accredited laboratory.
  • Covers all immunotherapy related bio-markers such as PD-L1, MSI and TMB.
  • Wholesome analysis of more than 417 genes enables use emergent of FDA approved therapies.
BETTER
FASTER
ECONOMICAL
SNVs/ INDELs
442 Genes
CNAs
417 Genes
FUSIONS
51 Genes
TMB
PDL1
MSI | MMR

Celldx™

Celldx™ is an intensive, accurate and actionable analysis of the genetic mutations present in a patient’s tumor to identify the most appropriate molecular targets for targeted therapy.

Several patients have taken advantage of this breakthrough technology and they are deriving unprecedented benefit from the analysis.

Features

Targeted Therapy : Evaluation of companion diagnostic therapies across several cancer indications, and clinical trial matching across all solid tumors.
Immunotherapy : Helps inform immunotherapy decisions by including genomic signatures such as microsatellite instability (MSI), tumor mutational burden (TMB) and PDL1 status.
Simplified Report : All results are provided in a simplified report, with indications for approved therapies and genomic highlights.
452 Genes (SNVs, CNAs, Fusions and Indels).
Turnaround time is less than 3 working days from the day we receive the tissue sample.

Comparison

Platform Parameters FoundationOne CDx* Celldx
NGS Number of Genes 324 452
SNVs + Indels 309 442
SNAs 309 417
Fusions 36 51
TMB
MMR
HRD
IHC PD-L1
(optional)
STR | IHC MSI
Patient Benefits TAT 2 Weeks 48 Hours
Cost

* FoundationOne®CDx are registered trademarks of Foundation Medicine, Inc.

SNVs + INDELs

ARAFBRCA1BRCA2CDKN1BFANCIH3F3AHIST1H3BKNSTRNMAGOHMAXMED12NOTCH3POLERAC1RAD51RAD51BRAD51CRAD51DRHEBRHOARNF43SLX4SPOPSTAT3U2AF1

SNVs + INDELs + CNAs

ABL1ABL2ACVR2AADAMTS20AFF1AFF3AKAP9AKT1AKT2AKT3ALKAPCARARID1AARID2ARNTASXL1ATF1ATMATRATRXAURKAAURKBAURKCAXLBAI3BAP1BCL10BCL11ABCL11BBCL2BCL2L1BCL2L2BCL3BCL6BCL9BCRBIRC2BIRC3BIRC5BLMBLNKBMPR1ABRAFBRD3BRIP1BTKBUB1BCARD11CASC5CBLCCND1CCND2CCND3CCNE1CD79ACD79BCDC73CDH1CDH11CDH2CDH20CDH5CDK12CDK2CDK4CDK6CDK8CDKN2ACDKN2BCDKN2CCEBPACHEK1CHEK2CICCKS1BCMPK1COL1A1CRBNCREB1CREBBPCRKLCRTC1CSF1RCSMD3CTNNA1CTNNB1CYLDCYP2C19CYP2D6DAXXDCCDDB2DDIT3DDR2DEKDICER1DNMT3ADPYDDSTEGFREML4EP300EP400EPHA3EPHA7EPHB1EPHB4EPHB6ERBB2ERBB3ERBB4ERCC1ERCC2ERCC3ERCC4ERCC5ERGESR1ETS1ETV1ETV4EXT1EXT2EZH2FAM123BFANCAFANCCFANCD2FANCFFANCGFASFBXW7FGF19FGF3FGFR1FGFR2FGFR3FGFR4FHFLCNFLI1FLT1FLT3FLT4FN1FOXL2FOXO1FOXO3FOXP1FOXP4FZR1G6PDGATA1GATA2GATA3GDNFGNA11GNAQGNASGPR124GRM8GUCY1A2HCAR1HIF1AHLFHNF1AHOOK3HRASHSP90AA1HSP90AB1ICKIDH1IDH2IGF1RIGF2IGF2RIKBKBIKBKEIKZF1IL2IL21RIL6STIL7RING4IRF4IRS2ITGA10ITGA9ITGB2ITGB3JAK1JAK2JAK3JUNKAT6AKAT6BKDM5CKDM6AKDRKEAP1KITKLF6KRASLAMP1LCKLIFRLPHN3LPPLRP1BLTFLTKMAFMAFBMAGEA1MAGI1MALT1MAML2MAP2K1MAP2K2MAP2K4MAP3K7MAPK1MAPK8MARK1MARK4MBD1MCL1MDM2MDM4MEN1METMITFMLH1MLLMLL2MLL3MLLT10MMP2MN1MPLMRE11AMSH2MSH6MTORMTRMTRRMUC1MUTYHMYBMYCMYCLMYCL1MYCNMYD88MYH11MYH9NBNNCOA1NCOA2NCOA4NF1NF2NFE2L2NFKB1NFKB2NINNKX2-1NLRP1NOTCH1NOTCH2NOTCH4NPM1NRASNSD1NTRK1NTRK2NTRK3NUMA1NUP214NUP98PAK3PALB2PARP1PAX3PAX5PAX7PAX8PBRM1PBX1PDE4DIPPDGFBPDGFRAPDGFRBPER1PGAP3PHOX2BPIK3C2BPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIM1PKHD1PLAG1PLCG1PLEKHG5PMLPMS1PMS2POT1POU5F1PPARGPPP2R1APRDM1PRKAR1APRKDCPSIP1PTCH1PTENPTGS2PTPN11PTPRDPTPRTRAD50RAF1RALGDSRARARB1RECQL4RELRETRHOHRICTORRNASELRNF2RNF213ROS1RPS6KA2RRM1RUNX1RUNX1T1SAMD9SBDSSDHASDHBSDHCSDHDSEPT09SETD2SF3B1SGK1SH2D1ASMAD2SMAD4SMARCA4SMARCB1SMOSMUG1SOCS1SOX11SOX2SRCSSX1STK11STK36SUFUSYKSYNE1TAF1TAF1LTAL1TBX22TCF12TCF3TCF7L1TCF7L2TCL1ATERTTET1TET2TFE3TGFBR2TGM7THBS1TIMP3TLR4TLX1TNFAIP3TNFRSF14TNK2TOP1TP53TPRTRIM24TRIM33TRIP11TRRAPTSC1TSC2TSHRUBR5UGT1A1USP9XVHLWASWHSC1WRNWT1XPAXPCXPO1XRCC2ZNF384ZNF521

GENE FUSIONS

AKT2ALKARAXLBRAFBRCA1BRCA2CDKN2AEGFRERBB2ERBB4ERGESR1ETV1ETV4ETV5FGFR1FGFR2FGFR3FGRFLT3JAK2KRASMDM4METMYBMYBL1NF1NOTCH1NOTCH4NRG1NTRK1NTRK2NTRK3NUTM1PDGFRAPDGFRBPIK3CAPPARGPRKACAPRKACBPTENRAD51BRAF1RB1RELARETROS1RSPO2RSPO3TERT

7 EASY STEPS TO CELLDX

1

Patient Enquiry

2

Response

Our representative will contact you in 6 Hrs

3

Help to choose the appropriate test

You can ask our representative to help in selection of the most appropriate test

4

Payment

5

Sample Transportation

We can assist you with the logistics
Sample requirement : FFPE block with tumor content >= 5% or 10 Unstained slides)

6

Sample Processing

7

Report Generation and Dispatch

DOWNLOAD BROCHURE + SAMPLE REPORT

PDF will be emailed

 

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