What can your DNA speak about your Health?

Human body cells have DNA, which influences many characteristics of the organism such as physical characteristics like height, colour of eyes, texture and colour of hair, etc. Human DNA encodes information for the processes that govern development, functioning and reproduction.

Gene represents certain specific stretches of DNA that are inherited from biological parents. These genes help to relate the characteristics of our parents and grandparents with us. They are the building blocks and everyone is born with a unique set of genes.

Personal Genome Analysis (PGA) from Datar Cancer Genetics Limited is a genetic test that can analyse each pair of genes and identify changes in genes.

About Personal Genome Analysis

Datar Cancer Genetics Limited currently offers Personal Genome Analysis (PGA), which is a genetic test can analyse each pair of genes and identify changes in chromosomes or genes. These tests are called predictive tests, diagnostic tests, carrier tests and pharmacogenetic tests, based on their purpose. It is a modern genetic screening test that is performed on the DNA obtained from a person’s blood & saliva.

Features Personal Genome Analysis

  • Determination of the disease predisposition of an individual
  • Determination of genetic makeup of an individual
  • Understand the impact of genes on diseases or conditions
  • DNA sequence and gives information about the disease or conditions

The need for DNA analysis

Condition Early Detection Late Detection
Lung Cancer Treatable. Lifestyle change can help avoidance of risk factors Decreased chance of cure
Diabetes Mellitus Can be managed with minimum collateral damage to other organs Extensive collateral damage to blood vessels, heart, nerves & eyes
Vitamin B12 Deficiency Can be resolved with dietary supplements / change in diet Anaemia, psychological disorders, damage to nerves


Likelihood of acquiring various common diseases

Personalized drug selection and treatment delivery

Carrier status for various genetic diseases such as color blindness, sickle cell anemia, etc

Familial risks for diseases such as breast cancer, colorectal cancer, etc.

Adverse reactions to drug molecules



Help you understand your genome, which is the genetic information encoded in your DNA

Tell you about your ancestry, inherited traits, and disease risks

Raise awareness of a particular risk so that necessary precautions could be taken in future

Increase surveillance and reduce the risk of actual development of diseases like diabetes or heart disease

Allow timely detection and early medical intervention

Point towards additional genetic tests which can be performed at later stage for more specific diagnosis


    Genetic risk for certain diseases

  • Abdominal aortic aneurysm
  • Asthma
  • Atrial fibrillation
  • Chronic kidney disease
  • Coeliac disease
  • Crohn’s disease
  • Diabetes mellitus type 1
  • Diabetes mellitus type 2
  • Gout
  • Hypertension (High blood pressure)
  • Kidney stones
  • Multiple sclerosis
  • Myocardial Infarction (Heart attack)
  • Peripheral arterial disease (Atherosclerosis)
  • Psoriasis
  • Rheumatoid arthritis
  • Venous thromboembolism
    Characteristics of metabolism

  • Blood sugar
  • Caffeine metabolism
  • HDL (good) Cholesterol
  • Iron
  • Lactose metabolism
  • LDL (bad) cholesterol
  • Potassium
  • Response to carbohydrates
  • Response to monounsaturated fats
  • Response to polyunsaturated fats
  • Response to saturated fats
  • Sodium
  • Triglycerides
  • Vitamin B12
  • Vitamin B6
  • Vitamin B9
  • Vitamin D
  • Vitamin E
  • Vitamin C
    Sports and recreation in tune with your genes

  • Achilles tendon
  • Biological ageing
  • Bone density
  • Muscle structure
  • Oxidative stress
  • Risk of being overweight
  • Strength training
    Genetically determined conditions

  • Alcohol addiction
  • Migraine
  • Nicotine addiction
  • Resistance to malaria (type Duffy)
  • Schizophrenia
  • Sickle cell disease
  • Thalassemia
  • Cardiomyopathy
  • Insulin Resistance
    Genetic risk factors for developing cancer

  • Basal cell carcinoma (Skin cancer)
  • Breast cancer
  • Chronic lymphocytic leukaemia
  • Colorectal cancer
  • Endometrial cancer
  • Lung cancer
  • Melanoma
  • Ovarian cancer
  • Prostate cancer
  • Thyroid cancer


How does analysis of genes help a person?

The understanding of specific genes which have been implicated in diseases / disorders / resistance help us to judge the manner in which our cellular mechanism is working. Such analysis gives timely warning of possible threats to health.

Do I have to do this test regularly?

No. The DNA which a person inherits remains constant from birth to death and its analysis is irrespective of the age at which it is conducted.

If I am in the high risk group, will I definitely get the disease?

The risk profile is the predisposition revealed by the analysis of a person’s DNA as compared to the population risk. Thus, a higher risk profile is a fair indicator of the probability of diseases. Besides being influenced by genes, environment also plays a role in the manifestation of the disease. Hence, by taking into account preventive measures and medical advice, we can do a lot to prevent diseases.

If one of my family member's DNA is analysed, why should I analyse DNA of others?

Each human being has a unique genetic makeup and there are no two persons who can ever have the same code. Thus, each member of the family will carry a separate genetic profile and accordingly will be susceptible / resistant to a disease in a different way, although, some characteristics within the family may be identical.

If I am going to get the disease any way, what is the use of knowing it?

Science and medicine have been progressing everyday to an extent where an early detection can assure timely intervention and cure. A late / wrong diagnosis can be fatal besides being financially burdensome.

Should I start taking medicines in anticipation of the onset of a disease for which I am found to be high risk?

Consulting your Doctor is a must before any medical intervention. Never take any prescription medicine or adopt a medical procedure or stop any medicine or alter any dosage on your own. The genetic analysis report is to be clinically correlated by a qualified medical professional before any consequential steps are adopted by you.

Is it possible that I have passed on my genetic characteristics to my children?

It is indeed possible, that you have passed on some of your genetic characteristics to your children.