Publications - Datar Cancer Genetics

Clinical utility of circulating tumor-associated cells to predict and monitor chemo-response in solid tumors.

Cancer Chemotherapy and Pharmacology volume 87, pages197–205 (2021).

Response to Pazopanib-Based Combination Regimen in a Case of FGFR3 Amplified Gastric Adenocarcinoma.

Volume 9, Issue 11, Published: 07 November 2021.

Re-establishing Responsiveness in a Case of Refractory Metastatic Rectal Cancer with a Personalized de novo Combination Regimen.

Volume 9, Issue 1, Published: March 10, 2021.

Angiogenesis Inhibitors in Personalized Combination Regimens for the Treatment of Advanced Refractory Cancers.

Front. Mol. Med, 20 September 2021.

Concordancy of Immunocytochemistry Profiling of Circulating Tumor Cells with Immunohistochemistry for Analysis of Therapeutically Relevant Biomarkers.

JCO 39, no. 15_suppl (May 20, 2021) 3047-3047. Published online May 28, 2021.

Excellent Response With Alpelisib and Bicalutamide for Advanced Salivary Duct Carcinoma With PIK3CA Mutation and High Androgen Receptor Expression—A Case Report.

JCO Precision Oncology no. 5 (2021) 744-750. Published online May 3, 2021.

Improved Treatment Outcomes by Using Patient Specific Drug Combinations in Mammalian Target of Rapamycin Activated Advanced Metastatic Cancers.

Published: Front. Pharmacol., 16 April 2021

Abstract PS2-40: Analytical and Clinical Validation of the Trucheck™ Platform for Diagnostic Triaging of Symptomatic Cases Suspected of Breast Cancer

DOI: 10.1158/1538-7445.SABCS20-PS2-40 Published February 2021

Abstract PS4-36: Non-Invasive Evaluation of Chemoresistance in Breast Cancers using Circulating Tumor Associated Cells

DOI: 10.1158/1538-7445.SABCS20-PS4-36 Published February 2021

Abstract PS3-13: Non-Invasive Screening for Breast Cancer Risk Based on Circulating Ensembles of Tumor Associated Cells

DOI: 10.1158/1538-7445.SABCS20-PS3-13 Published February 2021

Development and Validation of a Multigene Variant Profiling Assay to Guide Targeted and Immuno Therapy Selection in Solid Tumors.

Published: February 8, 2021.

Analytical and clinical validation of the TruCheck™ platform for diagnostic triaging of symptomatic cases suspected of colorectal cancer

DOI: 10.1200/JCO.2021.39.3_suppl.24. Published online January 22, 2021.

OFP01.05 Circulating Ensembles of Tumor Associated Cells Facilitate Efficient Triaging of Asymptomatic Individuals for Low Dose Computed Tomography

Volume 16, Issue 1, Supplement , S10, January 01, 2021.

PR01.01 Evaluation of Circulating Tumor Cells for Non-Invasively Discerning Lung Primary from Metastasis

Volume 16, Issue 1, Supplement , S40, January 01, 2021.

A Case Report of Androgen Receptor Inhibitor Therapy in Recurrent High-grade Serous Ovarian Cancer

Oncotarget. 2020; 11:4358-4363. Published online 17 November 2020.

Liquid Biopsy and Multi-analyte Testing Guided Treatment of HER2 Positive Periampullary Adenocarcinoma with Durable Complete Response after Trastuzumab Based Therapy

Oncotarget. 2020; 11:4195-4200. Published online 10 November 2020.

Clinical Utility of Circulating Tumor-Associated Cells to Predict and Monitor Chemo-Response in Solid Tumors

DOI: 10.1007/s00280-020-04189-8. Published online 10 November 2020.

Analytical and Clinical Validation of the Trucheck™ Platform for Diagnostic Triaging of Symptomatic Cases Suspected of Prostate Cancer

DOI: 10.1093/neuonc/noaa215.034. Published online 9 November 2020.

Multi Analyte Assay for Non-Invasive Diagnosis of Brain Tumors

DOI: 10.1093/neuonc/noaa215.034. Published online 9 November 2020.

Circulating Tumor Associated Cells in Breast Cancers are Resistance Educated towards Prior Anthracycline Treatments

VOLUME 138, SUPPLEMENT 1, S76, OCTOBER 01, 2020

Real-time Non-Invasive Chemoresistance Profiling of Circulating Tumor Associated Cells in Breast Cancers to Determine Resistance towards Mitotic Inhibitors

In Press

Non-Invasive Diagnostic Triaging of Suspected Lung Cancers based on Immunocytochemistry Profiling of Circulating Tumor Cells

Proceedings of the AACR IASLC 2020 Hot Topic Meeting: Liquid Biopsy. Available online October 01, 2020.

Mutational landscape and Tumor Mutation Burden of Indian NSCLC patients

Proceedings of the AACR IASLC 2020 Hot Topic Meeting: Liquid Biopsy. Available online October 01, 2020.

73P Anti-angiokinases in patient-specific combination regimens can improve outcomes in advanced metastatic cancers

MOLECULAR ANALYSIS FOR PRECISION ONCOLOGY| VOLUME 31, SUPPLEMENT 5, S1238, OCTOBER 01, 2020.

47P Improved treatment outcomes by using patient-specific drug combinations in mTOR activated advanced metastatic cancers

MOLECULAR ANALYSIS FOR PRECISION ONCOLOGY| VOLUME 31, SUPPLEMENT 5, S1232, OCTOBER 01, 2020.

Evaluation of Circulating Tumor Cell Clusters for Pan-Cancer Noninvasive Diagnostic Triaging

DOI: 10.1002/cncy.22366. Published online 30 September 2020.

Hallmark Circulating Tumour Associated Cell Clusters Signify 230 Times Higher One-Year Cancer Risk

DOI: 10.1158/1940-6207.CAPR-20-0322. Published online September 21, 2020.

Long Overall Survival in a Case of Refractory Stage IV Squamous Cell Carcinoma of Lung Treated with Personalized De Novo Combination Regimen

Clin Case Rep Int | Volume 4, Issue 1. Published online September 14, 2020.

Multi-Analyte Liquid Biopsies Based Treatment in Advanced Refractory Cancers

DOI: 10.1200/JCO.2020.38.15_suppl.e15623 Journal of Clinical Oncology 38, no. 15_suppl. Published online May 25, 2020.

Multi-Analyte Interrogation Based Treatment of Advanced Refractory Cancers

DOI: 10.1200/JCO.2020.38.15_suppl.e15624 Journal of Clinical Oncology 38, no. 15_suppl. Published online May 25, 2020.

Encyclopedic Tumor Analysis Guided Treatments with Conventional Drugs Outperform Available Alternatives in Refractory Cancers

Annals of Oncology. 2019 Nov 1;30(Supplement_7):mdz413-098

Clinical Utility of Encyclopedic Tumor Analysis to Treat Patients with Brain Metastasis in Refractory Cancers

Neuro-Oncology, Volume 21, Issue Supplement_6, November 2019, Pages vi59–vi60

Encyclopedic Tumor Analysis for Guiding Treatment of Advanced, Broadly Refractory Cancers: Results from The RESILIENT Trial

Oncotarget. 2019 Sep 24;10(54):5605

Adaptive, Iterative, Long-Term Personalized Therapy Management in a Case of Stage IV Refractory NSCLC

Journal of personalized medicine. 2019 Sep;9(3):34

Abstract B61: Encyclopedic Non-Invasive Liquid Biopsies for Differential Diagnosis in Prostate Cancer

DOI: 10.1158/1557-3265.LiqBiop20-B61 Published June 2020

Abstract B15: Circulating Tumor Cells Express Tissue Specific Antigens in Multiple Cancers

DOI: 10.1158/1557-3265.LiqBiop20-B15 Published June 2020

Encyclopedic Tumor Analysis Guided Personalized Treatments for Advanced Refractory Breast Cancer

DOI: 10.1055/s-0040-1714630. Published 16 July 2020

Abstract B17: An mRNA Signature that Accurately Discerns Gliomas from Healthy Individuals

DOI: 10.1158/1557-3265.LiqBiop20-B17 Published June 2020

Artificial Intelligence can Detect Lung Cancer from High Resolution Microscopic Images of Conditioned Peripheral Blood

Journal of Thoracic Oncology. 2019 Nov 1;14(11):S1138

Diagnosis of Gliomas Using Circulating Glial Cells

Neuro-Oncology, Volume 21, Issue Supplement_6, November 2019, Page vi153

PATH-37. Liquid Biopsy for Identification of Newly Diagnosed Glioma

Neuro-Oncology, Volume 20, Issue suppl_6, 1 November 2018, Pages vi166–vi167

MPTH-56. Algorithm Based Liquid Biopsy for The Diagnosis of Glioblastoma

Neuro-Oncology, Volume 18, Issue suppl_6, 1 November 2016, Page vi118

Liquid Biopsies to Enable Non-Invasive Real-Time Functional Chemoresistance Profiling in Solid Organ Cancers

DOI: 10.1200/JCO.2020.38.15_suppl.3525 Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020) 3525-3525. Published online May 25, 2020.

In Vitro Chemo Resistance Profiles of Circulating Glial Cells Replicate Chemo Characteristics of Tumor Tissue

Neuro-Oncology, Volume 21, Issue Supplement_6, November 2019, Page vi135

Tumor Infiltrating Lymphocytes Show in Vitro Cytotoxic Activity Against Tumor Cells in Multiple Cancers

DOI: 10.1200/JGO.2019.5.suppl.111 Journal of Global Oncology 5, no. suppl (October 07, 2019) 111-111

Presentation Link

Encyclopedic Tumor Analysis Guided Treatments with Conventional Drugs Outperform Available Alternatives in Refractory Head and Neck Cancers

April 1, 2020, Volume 106, Issue 5, Pages 1133–1134

Clinical Utility of Encyclopedic Tumor Analysis to Treat Breast Cancer Patients who have Failed Standard of Care Treatments

Volume/Issue: Volume 18: Issue 3.5; Online Publication Date: 20 Mar 2020

Clinical Utility of Encyclopedic Tumour Analysis to Treat Patients with Advanced Refractory Head and Neck Cancers

Annals of Oncology, Volume 30, Issue Supplement_9, November 2019, mdz431.008

mTOR Inhibitors in Combination Regimens Guided by Encyclopedic Tumour Analysis Show Superior Outcomes Compared to Monotherapy in Refractory Cancers

Annals of Oncology. 2019 Nov 1;30(Supplement_7):mdz413-115

Encyclopedic Tumor Analysis for Organ Agnostic Treatment with Axitinib in Combination Regimens for Advanced Cancers

Annals of Oncology. 2019 Oct 1;30(Supplement_5):mdz268-061

Clinical Efficacy of Combination Therapies with Androgen Receptor Antagonists for Treatment of Multiple Refractory Cancers

DOI:
10.1200/JGO.2019.5.suppl.115 Journal of Global Oncology 5, no. suppl (October 07, 2019) 115-115

Presentation Link

Encyclopedic Tumour Analysis (ETA) Guided Combination Regimens of Hormone Receptor Antagonists with Other Systemic Agents for Treatment of Refractory Cancers

Annals of Oncology. 2019 Nov 1;30(Supplement_7):mdz413-106

Liquid Biopsy in Periampullary Carcinoma

DOI:10.18203/issn.2456-3994.IntJMolImmunoOncol20164388

Molecular Interrogation of Glioblastoma Multiforme Tumors Identifies A Complex Network of Cell Signalling Pathways with Possible Therapeutic Implications

Neuro-Oncology. 2015 Nov 1;17(suppl_5):v91-

Abstract B16: Non-Invasive Liquid Biopsies for Guideline-Compliant Diagnostic Assessment in Ovarian Cancers

DOI: 10.1158/1557-3265.LiqBiop20-B16 Published June 2020

Abstract B62: Wholesome Non-Invasive Liquid Biopsies for Pharmacodiagnostic Work-Up in Breast Cancer

DOI: 10.1158/1557-3265.LiqBiop20-B62 Published June 2020

Encyclopedic Liquid Biopsies for Guideline-Compliant Diagnostic Work-up in Gastrointestinal Cancers

Journal of Clinical Oncology 38, no. 4_suppl (February 01, 2020) 799-799

PD-L1 Profiling of Circulating Tumor Cells for Immune Checkpoint Inhibitor Therapy in Head and Neck Cancers

Journal of Clinical Oncology 38, no. 5_suppl (February 10, 2020) 36-36

PD-L1 Profiling of Circulating Tumor Cells for Immune Checkpoint Inhibitor Therapy in Gastroesophageal Cancers

Journal of Clinical Oncology 38, no. 5_suppl (February 10, 2020) 29-29

PD-L1 Profiling of Circulating Tumour Cells is A Viable Companion Diagnostic for Checkpoint Inhibitor Therapy in Lung Cancer

Annals of Oncology, Volume 30, Issue Supplement_11, December 2019, mdz447.009

Diagnostic Non-Invasive Biopsy can Substitute Conventional Tissue Dependent Procedures in Suspected Cases of Lung Cancer

Journal of Thoracic Oncology. 2019 Nov 1;14(11):S1137-8

Prospective, Blinded Plasma Based Analysis for Diagnosis of Newly Diagnosed Glioma

Neuro-Oncology, Volume 21, Issue Supplement_6, November 2019, Pages vi157–vi158

Diagnostic Non-Invasive Biopsy can Substitute Conventional Tissue Dependent Procedures in Suspected Cases of Renal Cell Carcinoma

Volume 18, Issue 11, November 2019, Page e3515

Circulating Tumor Associated Cells in Head and Neck Cancers are Resistance Educated per Previous Chemotherapy Treatments

Volume 106, Issue 5, P1121, April 01, 2020

Abstract P6-10-11: In Vitro Chemo Interrogation of Viable Circulating Tumor Associated Cells from Breast Cancer Patients

DOI: 10.1158/1538-7445.SABCS19-P6-10-11 Published February 2020

Effect of Previous Chemotherapy Treatments on Circulating Tumor-Associated Cells in Colorectal Cancer

Journal of Clinical Oncology 38, no. 4_suppl (February 01, 2020) 194-194

Circulating Tumor-Associated Cells in Lung Cancers Are Resistance-Educated per Previous Chemotherapy Treatments

Journal of Thoracic Oncology. February 2020; Volume 15, Issue 2, Supplement, Page S37

Circulating Tumour Associated Cells in Esophageal Cancers are Resistance Educated Per Previous Chemo Treatments

Annals of Oncology. 2019 Nov 1;30(Supplement_7):mdz413-050

In Vitro Functional Interrogation of Viable Circulating Tumor Associated Cells (C-TACs) for Evaluating Platin Resistance

Annals of Oncology. 2019 Oct 1;30(Supplement_5):mdz268-099

Abstract A49: Viable Circulating Ensembles of Tumor-Associated Cells Persist in Pretreated Patients with Solid Organ Cancers showing no Radiologically Detectable Disease

DOI: 10.1158/1557-3265.LiqBiop20-A49 Published June 2020

Circulating Microtumors: A functional Hallmark for Cancer Detection and Management

DOI: 10.1200/JCO.2020.38.15_suppl.3544 Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020) 3544-3544. Published online May 25, 2020.

Viable Circulating Ensembles of Tumor Associated Cells Persist in Patients with No Radiologically Detectable Disease After Treatment in Head and Neck Cancer

April 1, 2020, Volume 106, Issue 5, Page 1133

Circulating Ensembles of Tumor-Associated Cells in Genitourinary Cancers

DOI: 10.1200/JCO.2020.38.6_suppl.718 Journal of Clinical Oncology 38, no. 6_suppl (February 20, 2020) 718-718

Abstract P4-01-17: Viable Circulating Ensembles of Tumor Associated Cells Persist in Patients with No Radiologically Detectable Disease after Treatment in Breast Cancer

DOI: 10.1158/1538-7445.SABCS19-P4-01-17 Published February 2020

Abstract P4-01-05: Circulating Ensembles of Tumor Associated Cells for Detection of Breast Cancer

DOI: 10.1158/1538-7445.SABCS19-P4-01-05 Published February 2020

Circulating Ensembles of Tumor-Associated Cells in Gastrointestinal Cancers

Journal of Clinical Oncology 38, no. 4_suppl (February 01, 2020) 808-808

Circulating Ensembles of Tumor-Associated Cells Are Ubiquitous in Lung Cancers

Journal of Thoracic Oncology. February 2020; Volume 15, Issue 2, Supplement, Page S16

Circulating Ensembles of Tumor Associated Cells: A Redoubtable New Systemic Hallmark of Cancer

30 November 2019